Bexxar Therapy

You have been scheduled for a bexxar therapy, which is a treatment for CD20 positive follicular non-Hodgkin’s lymphoma. Bexxar is considered a dual action treatment for non-Hodgkin’s lymphoma because it attacks cancer cells in two ways, providing both radiation therapy and immunotherapy in a single treatment.

Preparation for the procedure:
  Twenty four hours prior to the dosimetric dose (the first infusion) you need to take 130mgs of SSKI in a tablet form. This SSKI protects your thyroid from absorbing the iodine used for the treatment. You will continue to take one tablet a day of the SSKI for twenty five to thirty days. Please inform the technologist if you are pregnant or breast feeding. This treatment is not recommended for women who are pregnant or breast feeding.


What to expect:
Visit 1: Once you are here you will be brought to an exam room where we will have you lie down on a table. You will then be given Tylenol (to help prevent fever) and Benadryl (to help prevent allergic reactions or flu-like symptoms). An IV will be started in your arm in order to give you the treatment. Thirty minutes after the Tylenol and Benadryl a sixty minute infusion of Tositumomab, the monoclonal antibody used in Bexxar will be given. You will then be given a twenty minute infusion of Tositumomab plus a small amount of Iodine-131. Following this twenty minute infusion you will have an image taken on a gamma camera.
Visit 2: One to two days later you will have another image taken on a gamma camera.
Visit 3: Six or seven days later you will have another image taken on a gamma camera.
Visit 4: Once you are here you will be brought to an exam room where we will have you lie down on a table. You will then be given Tylenol (to help prevent fever) and Benadryl (to help prevent allergic reactions or flu-like symptoms). An IV will be started in your arm in order to give you the treatment. Thirty minutes after the Tylenol and Benadryl a sixty minute infusion of Tositumomab, the monoclonal antibody used in Bexxar will be given. You will then be given a twenty minute infusion of Tositumomab plus the treatment dose of Iodine-131.

Because of the amount of radiation from the I-131 given to you on visit 4 you will need to follow strict guidelines following the treatment for as many as ten days. These will be discussed with you during your first visit if not beforehand.

The follow up for your care will continue to be provided by your own Oncologist.

Your questions and comments:
call (805) 563-5870.

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